Laminar flow cabinet FBB IVF

Inovated laminar flow cabinet specially designed for IVF centers. The set is made up of components that are tested in practice and provide optimum works with cells and tissues.

Laminar flow cabinet FBB-IVF provides excellent protection against particle and bacterial contamination of processed tissues and cells.

LAMINAR FLOW CABINET CONSTRUCTION

Cabinet workspace provides cleanliness class A according to EC GMP Volume 4, Annex 1. Thanks to a low vibration level provide an ergonomically ideal conditions for working with the microscope.

Operation of the workstation is controlled by the state-of-the-art SMART control system CR2000, which is inspired by requirements fo 4.0 industry. This control system ensures fully automatic operation of the device, local control and also remote control. Workstation it is possible to  control via touch screen or remotely via mobile devices. The display shows all important operating parameters. The flow velocity and pressure drop at the filter are continuously measured and evaluated. These information is processed by a microprocessor unit that optimizes workstation performance, including the fan. This solution ensures compensation of pressure drop increase as the working filter becomes clogged. Compared to other similar devices, operating costs are up to tens of percent lower. The airflow velocity is programmable in the range of 0.2 to 0.6 m/s. The user interface is designed to be as user-friendly as possible. Control of basic requirements, such as switching modes (stand-by, attenuation, operation), or heating surfaces, lighting, etc. is realized from the one single home screen. The CR2000 control system is continuously updated with new features and meets the latest GMP requirements. 

Audittrail and monitoring are available as part of the new firmware. It is a professional solution that cover the needs of modern quality management. All important changes, alarms and parameters are registered.

During the development great emphasis was also placed on safety. Access to the control system is differentiated according to the level of access rights. Any remote connection is indicated on the screen. Non-conforming states are displayed and recorded within the auditrail, or sent to the responsible persons' email. Electrical safety protecting of the user is enhanced by an integrated residual-current circuit breaker (RCCB).

Workspace surfaces are smooth and easy to clean. All finishes comply with the strict conditions of clean room standards EN ISO 14644. The working desk is made of high quality stainless steel.

The device boasts a very low level of vibration. This is ensured primarily by the use of a quality fan, solid construction and the use of vibration absorbing elements (eg anti-vibration inserts).

The required particle cleanliness in the working area is ensured by a high-efficient filter with an efficiency of 99.995%, ie. class H14 acc. to EN 1822:2009 and ISO 45 Hd acc. to ISO 29463:2011. The laminar cabinet is equipped with a maintenance-free, powerful fan. This allows the maximum filtration capacity of the filters to be used. Under standard laboratory conditions, the installed filters will last many years without having to replace them.

 Recommended combination:

• laminar flow cabinet FBB-IVF
• microscope NIKON SMZ745 (800, 1000) with P-DSL32 stand integrated in to the heating surface, or Olympus SZX7 (SZX10, SZX16) with SZX2-ILLTS LED Base
• incubator CO2 Labotect C16 or Selutec TECO 10

The above technological devices are recommended. As a direct manufacturer we are able to provide extra customization and integrate into the cabinet the technology of your choice (including LCD panels, all-in-one PC, video cameras, microscopes and incubators from other producers, etc.).

HEATING SURFACE WITH OR WITHOUT MICROSCOPE INTEGRATION

For works with heat-sensitive biological material, the recessed heating surface (600x290mm) is integrated into the working desk. This heating surface achieves excellent stability and homogeneity. The top of the heating surface is made of the same material as the surrounding workdesk surface, ie high-quality stainless steel. The basis of the heating surface is a special heated heating glass of a size covering the entire surface. Thanks to this solution, uniform heating is ensured both in the heating surface and in the quartz glass for the microscope.

The heating surface temperature is controlled by means of precise PID regulation within the CR2000 SMART control system. The temperature is measured continuosly with a high precision temperature sensor. The evaluation is continuous and the latest algorithms are used. This ensures fast heating of the heating surface without significant overshoot over the set temperature. The heating surface can be controlled both locally and remotely, both within the local data network and via the Internet. The user is able to control both the setpoint temperature setting and is able to enter alarms according to GMP standard.

Is recommended to integrate the NIKON SMZ (745, 800, 1000, 1250) microscope with P-DSL32 stand as the best solution. This microscope achieves top performance. In addition to high magnification and high working height, excellent ergonomics.

Another recommended solution is the integration of OLYMPUS SZX7 microscope (SZX10, SZX16). These microscopes achieve top parameters mainly with brilliant optics and optimization of observation methods. Along with excellent ergonomics, they also offer high magnifications and long working distances of samples from the objectives.

The concept of the solution of this workstation allows the integration of the illumination developed by microscope manufacturer. As a result, image quality is maximized, and state-of-the-art technologies (such as OCC) can be used. And even upgrades are possible in the future. 

INCUBATOR CO2 

For storage cells is in the rear panel of the cabinet integrated an incubator CO2 brand Labotect C16 or Selutec TECO 10 with the protection of the CO2 atmosphere. This 16-liter incubators are equipped with two shelves and alarm.

REFERENCES

Our solutions are the first choice for important IVF centers in Europe. 

Control and management by SMART CR2000

The control and management of the workstation is provided by the state of the art CR2000 smart control system. This system ensures trouble-free operation of the device in 24/7 mode. Control is possible both through the large touch screen and using mobile devices and PC. The touch screen with IPS technology reacts even through laboratory gloves. The display shows all important parameters and states. The speed of the air flow in the working space, temperature in the working space (optional), pressure drop on the filter. These signals are processed by a microprocessor unit, which optimizes the performance of the device accordingly. User interface is intuitive. The control system allows the setting of timers for switching the device on and off, including the selection of the operating mode. Changing alarm settings, timers and other parameters and functions are user-adjustable.

Optional accessories

The cabinet can be modified / equipped with the following optional accessories:

• Magnetic tool holder on the rear work wall
  upto 19" LCD Screen or all-in-one recessed in the rear working space wall. Convenient for microscope application, visualization, gravimetric preparation, SOP, med info system
• Armrest height-adjustable ergonomic armrest (across the entire width of the workspace) 
• Ionization system for the removal of electric charge from the work area
• Electrical sockets, data sockets, USB sockets, etc.
• Front panel color (blue, white)
• Uninterruptible power supply (UPS) to ensure protection against electric power blackout and disturbances in the power network (including compensation of the local variations in the mains voltage and frequency)
• Cabling organizer - to hide the cabling under the worktop, can be supplied including a socket strip with five inputs
• Electric height adjustable standing 
• Webcam in the workspace with the possibility of streaming to the local data network
• Shelf, PC compartment, Pull-out keyboard tray
• Client technology integration.

On customer's request, it is also possible to make individual modifications, such as different material or color design or other possible design modifications, or installation of additional special accessories, according to customer requirements. Please consult any modifications in advance.

Maintenance, service

The cabinet is designed as maintenance-free. Cabinet control is simple and intuitive. The responsible person of the user has the opportunity to change the basic parameters, timers, and alarm limit settings. Service, firmware update, sensor calibration, etc. is accessible for service technicians of the CR2000 system.  Thanks to CR2000, some service, troubleshooting, and training, can be performed remotely. 

Qualification and monitoring

As part of the output control and installation, the qualification of the cabinet is performed. At least in the scope of operational qualification (OQ). At the client's request, it can be extended by installation (IQ) and performance qualification (PQ). In accordance with the requirements of standards and regulation, we also perform regular revalidations (qualifications) and monitoring.

Transport and installation

The cabinet is supplied and serviced by the manufacturer or certified distributors. The cabinet can be transported through a standard door 80 cm wide.

Warranty

Lifetime warranty on spare parts availability and service support (at least for 10 years). Standard warranty period is 24 months.